Association entre typage HLA et Maladies Auto-Immunes

Association entre typage HLA et Maladies Auto-Immunes
ASSOCIATION BETWEEN THE PRESENCE OF VARIOUS HLA MARKES AND SELECTED AUTOIMMUNE DISEASES

DISEASE	ASSOCIATED HLA MARKER	RELATIVE RISK OF DISEASE
Ankylosing spondylitis spa :spondylarthrite	B27	87.4
Reactive arthropathy, including Reiter’s syndrome flr	B27	37.0
Rheumatoid arthritis ra pr : polyarthrite rhumatoide	DR 4	4.2
Behçet’s syndrome	B51	3.8
Systemic lupus erythematosus led lead	DR 3	5.8
Insu in-dependent (type 1) diabetes did	DR 3	3.3
mellitus	DQB1*0201	2.4
	D 4	6.4
	DQB1*0302	9.5
	DR 2	0.19
Idiopathic Addison’s disease	DR 3	6.3
Graves’ disease	DR 3	3.7
Hashimoto’s disease	DR 11	3.2
Postpartum thyroiditis	DR 4	5.3
Celiac disease : Maladie caeliaque	DR 3	10.8
	DQB1*0201	6.0–10.0
	DQA1*0501
	DR 7, 11
	DR 7, DQB1*0201
	DR 11, DQA1*0501
Dermatitis herpetiformis	DR 3	15.9
Sicca syndrome	DR 3	9.7
Myasthenia gravis	DR 3	2.5
Myasthenia gravis	B8	3.4
Idiopathic membranous g omeru-	DR 3	12.0
Goodpasture’s syndrome	DR 2	15.9
Multiple sclerosis	DR 2	4.1
	DR B1*1501
	DR B5*0101
	DQB1*0602
Pemphigus vulgaris (among Ash-kenazi Jews)	DR 4	14.4
Psoriasis vulgaris	Cw6	13.3
Birdshot retinochoroidopathy	A29	109.0